Tonight 20:00 Live on Sky Sports 1
Top Industry Price
2 or More Goals - Robin Van Persie - 10/3
Arsenal odds to win - 4/9
Draw - 7/2
Newcastle odds to win - 7/1
Mikel Arteta and Aaron Ramsey should return for Arsenal after respective head and ankle injuries.
Yossi Benayoun has overcome illness and Andre Santos is back in training after a long-term ankle problem.
Newcastle's Peter Lovenkrands could miss the rest of the season after suffering a suspected ruptured thigh muscle against Sunderland.
There has been a broad range of words used to describe Arsenal so far this season - the latest must surely be "comeback kings".
The Gunners have come from behind to win in their last three Premier League matches, including against Tottenham and Liverpool.And in the Champions League in midweek, they nearly pulled off the biggest of the lot when they went 3-0 up against AC Milan before narrowly failing to overturn a 4-0 first-leg deficit.
Arsenal's Champion League dreams may be over for another year but they are at least back on course to book a spot in Europe's elite club competition next season, something that looked much less likely before Christmas.
Arsene Wenger's side are looking for a fifth consecutive Premier League victory but they will be wary of Newcastle, who have surpassed expectations this season. The Magpies are without a win in three games, but snatching a last-gasp draw in the Tyne-Wear derby last weekend will have given them a lift ahead of their visit to the Emirates, where they won last season.
And when it comes to fightbacks, Newcastle can stand toe-to-toe with the Gunners - in the reverse fixture last season, the Magpies were 4-0 down but then scored four goals in 19 minutes to earn a draw in one of the greatest comebacks in Premier League history.
Arsenal have won six of the last eight times they have hosted Newcastle in the Premier League (W6, D1, L1) but lost 1-0 in this fixture last season.
The Gunners have had a man sent off in each of their last three meetings with Newcastle - Gervinho, Abou Diaby and Laurent Koscielny.
Arsenal are looking for a fifth successive Premier League victory.
The Gunners have come from behind to win in each of their last three league matches. In total, they have come from behind to win five times in this season's top flight. No club in Premier League history has ever come from behind to win four consecutive matches.
Arsenal have scored a stoppage-time goal in three of their last four league matches.
Robin van Persie's 25 league goals this season include scoring in each of the club's last four home league matches (six goals).
Newcastle have lost three of their last four away matches in the Premier League.
The Magpies have taken just one point from nine in visits to London this season, losing at Tottenham and Fulham, and drawing at QPR.
Alan Pardew's side have conceded five goals in two of their last three away league matches, losing 5-2 at Fulham and 5-0 at Tottenham.
Demba Ba has scored 16 Premier League goals this season - the most by a Newcastle player in a single season since Alan Shearer (22 goals) in 2003/04.